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Oligonucleotide Synthesizer Systems
OligoProcess™ oligonucleotide synthesizer systems are custom designed for reliable and cost-effective industrial production. They use novel flow-through column technology to keep amidite consumption to a minimum.
OligoProcess systems are validated industrial scale processes for oligonucleotide production. They are installed and qualified for GMP production by GE Healthcare personnel.
OligoProcess systems offer:
- Guaranteed application performance
- Proven technology from a leading supplier to the therapeutic oligonucleotide market.
- IQ/OQ documentation.
- Verification synthesis of mutually agreed preset specifications.
- Seamless scale-up from ÄKTA™ oligopilot plus and OligoPilot™ 400 to OligoProcess systems.
- Cost-efficient production enabled by novel flow-through technique.
- 21 CFR part 11 compatible UNICORN™ software.
- Compliance with NFPA explosion-proof design regulations in North America and the ATEX directive in Europe.
- Production ranges from 50 mmol to over 1 mol, or more, of therapeutic oligonucleotides.
- The systems are explosion-proof and constructed with industrial-grade components that can withstand harsh synthesis chemicals.
OligoPilot 400 and ÄKTA oligopilot:
- Both OligoPilot 400 and ÄKTA oligopilot plus are available for intermediate-scale synthesis and research and process development.
Find out more in our oligonucleotide synthesis section.
CBS also supplies Pre Post Synthesis Module (PPSM) systems for automated column packing and unpacking, and post synthesis on-column cleavage of oligonucleotides. Columns for oligosynthesis are produced in conjunction with the systems to guarantee system compatibility and application performance.
Imagined - Custom designed bioprocessing solutions to your production requirements.
Delivered - Specification, design & manufacturing to installed, validated & tested systems.
Supported - Support services offered to clients with customized BioProcess solutions. | 
