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AVB Sepharose High Performance

  • Fast, one-step purification of adeno associated viruses of several subclasses
  • Prepacked HiTrap™ columns for simple operation with a syringe, pump or chromatographic system.
  • Excellent scalability
Adeno associated viruses are of increasing interest as potential vectors for gene therapy. To enable the use of AAV in clinical applications, an efficient and high quality production process is needed, including the downstream purification process. The process needs to be robust, with high yields, high purity, and low leakage of ligand. In current purification protocols density gradient centrifugation is typically used, followed by several chromatography steps, giving a process with low yield and poor scalability.

Read more in AVB Sepharose High Performance data file.

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