Highlights

G1S Cell Cycle Phase Marker Assay for dynamic, non-toxic reporting of cell cycle status in living cells.
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Cell Cycle
The cell cycle represents the most fundamental and important process in eucaryotic cells. An ordered set of events, culminating in cell growth and division into two daughter cells, the cell cycle is tightly regulated by defined temporal and spatial expression, localization and destruction of several cell cycle regulators. Cyclins and cyclin-dependent kinases (CDK) are major control switches for the cell cycle, causing the cell to move from G1 to S or G2 to M phases. Because cell cycle dysregulation is such a common occurrence in neoplasia, the opportunity to discover new targets for anticancer agents and improved therapeutics has been the focus of intense interest.
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