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Applications
Cytostar-T
Applications
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Applications


A wide variety of applications for Cytostar-TTM scintillating microplates have already been identified ranging from receptor-ligand interactions to studies of cell proliferation, drug uptake and efflux and in situ quantitation of mRNA induction. Cytostar-T scintillating microplates can also be treated with appropriate coatings for suspension cells (for example, poly-D lysine) and Amersham Biosciences would be pleased to discuss customized coatings for specific project needs.

More details can be found in the ordering table below, click on the code number for further information.

The Cytostar-T plates are also available as part of ready-configured kits for ease of use. Applications such as thymidine or leucine uptake measurements are available.

Cellular metabolism – metabolite transport (e.g. glucose), drug uptake/excretion.

Uptake of [14C] Docetaxol in control (SKMES-1) cells, measured in Cytostar-T scintillating microplates

Cell viability – measurement of cell proliferation and cytotoxicity.


Uptake of [14C] Thymidine in HeLa cells

Cell biology – receptor binding, cell motility and signal transduction, including arachidonic acid release, ion channel flux and gene expression.

Release of [14C] arachidonic acid from CHO M1 cells exposed to McN-A343, measured in Cytostar-T scintillating microplates


Cytostar-T Plates are either individually wrapped in packs of 5 or in sleeves of 20, a high-throughput screening pack contains 100 plates.