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Biotrak Assays for Inflammantory Bowel Disease, Crohn’s Disease, Ulcerative Colitis

Categories of MediatorsBiotrak™ Assays
Pro-inflammatory cytokines -stimulate immune response rapidly)TNFa, IL-1a, IL-1b, IL-6, IL-12
Th1 cytokines - initiate cellular immunity IL-2, IFNg, TNFb
Chemokines - attract inflammatory cells to site IL-8, MCP-1
MMPs - degrade tissueMMP-1 to MMP-13, TIMPs
Complement Factors (Innate immunity, 1st line of defence) C3a, C4a, C5a
T-cell proliferation IL-2
Inflammatory Mediators (pain, swelling, fever)PGE2, LTB4, TXB2
Anti-inflammatory agents (balance the system)Th2 cytokines (IL-4, IL-5, IL-10, IL-13) TGFβ, cAMP, cGMP
Induce expression of adhesion moleculesTNFa, IL-1b
Chemokine gradient affecting migration of leucocytes into mucosa and submucosa IL-8, RANTES,MCP-1
Stimulation of apoptosis inhibition PGE2



Pro-inflammatory cytokines -stimulate immune response rapidly)

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Th1 cytokines - initiate cellular immunity

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Chemokines - attract inflammatory cells to site

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MMPs - degrade tissue

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Complement Factors (Innate immunity, 1st line of defence)

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T-cell proliferation IL-2

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Inflammatory Mediators (pain, swelling, fever)

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Anti-inflammatory agents (balance the system)

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Induce expression of adhesion molecules

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Chemokine gradient affecting migration of leucocytes into mucosa and submucosa

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Stimulation of apoptosis inhibition

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    Consult the Technical Support section for your information needs, imcluding pack leaflets.

    See our assay accessories section to enhance your assay performance

    Record your results with the Biotrak Plate Reader

    View our complete list of Biotrak Immunoassays


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    Disease States Assay Poster today!