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Biotrak Assays for Arthritis Rheumatoid, Arthritis, Osteoarthritis
| Categories of Mediators | Biotrak™ Assays |
Pro-inflammatory cytokines -
stimulate immune response rapidly | TNFa, IL-1a, IL-6, IL-12 |
| Th1 cytokines - initiate cellular immunity | IL-2, IFNg, TNFb |
| Chemokines - attract inflammatory cells to site | IL-8, MCP-1 |
| MMPs - degrade bone/extracellular matrix | MMP-1 to MMP-13, TIMPs |
Complement Factors
(Innate immunity - 1st line of defence vs pathogen) | C3a, C4a, C5a |
| Maturation Factors - synthesis of defence cells | IL-3, GM-CSF |
| Inflammatory Mediators (pain, swelling, redness, fever) | PGE2, LTB4, TXB2 |
| Anti-inflammatory agents Th2 cytokines (balance the system) | (IL-4, IL-5, IL-10, TGFβ, cAMP, cGMP) |
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Pro-inflammatory cytokines - stimulate immune response rapidly
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Th1 cytokines - initiate cellular immunity
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Chemokines - attract inflammatory cells to site
Return to top
MMPs - degrade bone/extracellular matrix
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Complement Factors (Innate immunity - 1st line of defence vs pathogen)
Return to top
Maturation Factors - synthesis of defence cells
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Inflammatory Mediators (pain, swelling, redness, fever)
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Anti-inflammatory agents Th2 cytokines (balance the system)
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Pack Leaflets
