The tables below link to published papers and articles in the cell biology area. They are displayed in product areas, please use the links to navigate to each section where the references are shown.



Amersham Biosciences Publications.

Products	Number of references
Cardiovascular	2
Cytokines	2
Eicosanoids	3
MMP's	1
Second Messenger	10

Cell Biology area Publications that have used Biotrak Products.

Products	Number of references
Cardiovascular	4
Cytokines	5
Eicosanoids	12
MMP’s	8
Second Messenger	35
Signal Transduction	35
Cell Proliferation	17
Steroids	1
Metabolism & Toxicology	7
Antibodies & Reagents	23

SPA and Cytostar-T references are available here



Amersham Biosciences publications.


Cardiovascular

1. Plumpton, C., Horton, J.K., Kalinka, S., Martin, R.C., Davenport A.P., Effects of phosphoramidon and pepstatin A on the secretion of endothelin-1 and big endothelin-1 in human umbilical vein endothelial cells: measurement by two-site ELISAs. B. J. Pharmacol., (Suppl.) 112 , p.114. 1994.
2. Plumpton, C., Kalinka, S., Martin, R.C., Horton, J.K., Davenport, A.P., Effects of phosphormamidon and pepstatin A on the secretion of endothelin-1 and big endothelin-1 by human umbilical vein endothelial cells: measurement by two-site enzyme-linked immunosorbent assays. Clinical Science, 87, pp.245-251, 1994.

Cytokines

1. Horton, J.K., Kalinka, S., Martin, R.C., and O’ Beirne, G. Effect of interleukin-1b on the generation of IL-6 in ECV304 cells, direct, quantitative, intracellular measurement with enzyme-linked immunosorbent assay. Mediators Inflammation, 8, p.80 (Suppl), 1999.
2. Horton, J.K., Kalinka, S., Martin, R.C., O’Sullivan, M.J., Ismail, R., Phipp, C., Baxendale, P.M. Effect of interleukin-1b on the generation of interleukin-6 in ECV304 cells: direct, quantitative, intracellular measurement by enzyme-linked immunosorbent assay. Immnunology, 92, p.65 (Suppl), 1997.

Eicosanoids

1. Horton, J.K., Williams, A.S., Smith-Phillips, Z., Martin, R.C., and O’ Beirne, G. Direct intracellular measurement of prostaglandin (PG)E₂ synthesis in cultured mouse fibroblast cells: effect of cyclooxygenase inhibitors. Br. J. Pharmacol., 126, p.154 (Suppl), 1999.
2. Horton, J.K., Williams, A., Smith-Phillips, Z., Martin, R., and O’ Beirne, G. Effect of anti-inflammatory drugs on intracellular prostaglandin E₂ expression and cyclooxygenase activity. Mediators Inflammation, 8, p.16 (Suppl), 1999.
3. Horton, J.K., Williams, A.S., Smith-Phillips, Z., Martin, R. C., O’ Beirne, G. Intracellular Measurement of Prostaglandin E₂: Effect of Anti-Inflammatory Drugs on Cyclooxygenase Activity and Prostanoid Expression. Anal. Biochem., 271, pp.18-28, 1999.

MMP’s

1. Blain, E.J., Gilbert, S.J., Wardale, R.J., Capper, S.J., Mason, D.J., Duance, V.C. Up-regulation of matrix metalloproteinase expression and activation following cyclical compressive loading of articular cartilage in-vitro. Arch. Biochem. Biophys., 396 (1), p.49-55,2001.

Second Messenger

1. O’ SULLIVAN, M.J., CAPPER, S., WHATELEY, J. et al., Immunoassay Applications in Life Science Research. In: Wild, D., (Ed) The Immunoassay Handbook, Nature Publishing Group, pp.817-845, 2001.
2. HORTON, J.K., SEDDON, L.J., WILLIAMS A.S. BAXENDALE P.M. A method for measuring intracellular cyclic AMP levels with immunoassay technology and novel, cellular lysis reagents. Br. J. Pharmacol. (Suppl), 123, p.31, 1998.
3. Conversion of the cAMP direct screening assay to a 384 well format. Amersham Biosciences, Proximity News 57, 1998.
4. ICHIKAWA et al., Identification and role of adenylyl cyclase in auxin signalling in higher plants. Nature, 390, pp.698-701, 1997.
5. Direct quantitation of intracellular levels of cAMP-eliminating lengthy extraction processes. Nycomed Amersham, Life Science News 23, 1997.
6. Direct and in situ measurement of cAMP in cell culture with scintillation proximity radioimmunoassay. Amersham Biosciences, Proximity News 34, 1997.
7. High throughput screening for cAMP formation by scintillation proximity radioimmunoassay. Amersham Biosciences, Proximity News 23, 1996.
8. HORTON, J.K., BAXENDALE P.M., Mass measurements of cyclic AMP formation by radioimmunoassay, enzyme immunoassay and scintillation proximity assay. In: Kendall, D.A., and Hill, S.J., (Eds) Meth. in Mol. Biol, 41, pp.95-105, 1995.
9. HORTON, J.K., SMITH, L., ALI, A., et al., High throughput screening for cAMP formation by scintillation proximity radioimmunoassay. Packard Instrument Company TopCount Topics 21, pp.1-4, 1995.
10. HORTON, J.K., MARTIN, R.C., KALINKA, S., et al., Enzymeimmunoassays for the estimation of adenosine 3’,5’cyclic monophosphate and guanosine 3’,5’cyclic monophosphate in biological fluids. J. Immunological Methods, 155, pp.31-40, 1992.

Cell biology area publications that have used Biotrak products.

Cardiovascular

1. KUGLER, C.F.A., et al.,The role of endothelin-1- like immunoreactivity in cognitive dysfunction and long-term morbidity of patients with cerebral arteriosclerosis.Poster presented at the III European congress of Gerontology, 30^th August-2^nd September, 1995.
2. PFEIFER, P, H., et al., Possible mechanism for in-vitro complement activation in blood and plasma samples: futhan/EDTA controls in-vitro complement activation. Clin. Chem., 45, pp. 1190-1199, 1999.
3. HUMBLES, A. A., LU, B., NILSSON, C. A., et al, A role for the C3a anaphylatoxin receptor in the effector phase of asthma. Nature, 406, pp. 998–1001, 2000.
4. FOGARI, R., TETTAMANTI, F., MUGELLINI, A., et al., Endothelin in mild to moderate essential hypertension. Relationship between ambulatory and clinical blood pressure values, Journal of Human Hypertension, 8, 10, pp. 761-764, 1994.

Cytokines

1. KASAHARA, T., et al., Interleukin-8 and monocyte chemotactic protein-1 production by a human glioblastoma cell line, T98G in co-culture with monocytes: involvement of monocyte-derived interleukin-1alpha. Eur. Cytokine Network, 9 (1), pp.47-55, 1998.
2. USAWATTANAKUL, W., et al., Detection of cytokine in dengue haemorrhagic fever patients in Thailand. Mahidol University Annual Research Abstracts,The Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
3. TUJULIN, E., et al., Early cytokine induction in mouse P388D1 macrophages infected by Coxiella burnetti. Vet. Immunology and Immunopathy, 68, pp.159-168, 1999.
4. LORD, G. M., MATARESE, G., HOWARD, J. K., et al., Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression. Nature, 394, pp. 897–901, 1998.
5. HANEJI, N., NAKAMURA, T., TAKIO, K., et al., Identification of alpha-fodrin as a Candidate Autoantigen in Primary Sjögren's Syndrome. Science, 276, pp. 604-607, 1997.

Eicosanoids

1. SAUNDERS, M, M., et al., Differential effect of oscillating fluid flow on cytosolic cacium and prostaglandin in osteoblastic ROS 17/2.8 cells. Poster presented at the 46^th annual meeting, Orthopaedic Research Society, Orlando, Florida, March 12^th-15^th, 2000.
2. HINUMA, S., et al., A prolactin-releasing peptide in the brain. Nature, 393, pp.272-276, 1998.
3. GIESE, A., et al., Thromboxane synthase regulates the migratory phenotype of human glioma cells. Neuro-Oncology, 1999.
4. DESHPANDE, G, G., et al., Heat stress is assocoiated with decreased lactic acidema in rat sepsis. Crit. Care., 4, pp.45-49, 2000.
5. NAPOLI, E and FRANCO, N. Thromboxane A2 production in the pathogenesis of diabetic complications. Minerva Endocrinol., 23, pp.1-5, 1998.
6. GILROY, D. W., COLVILLE-NASH, P. R., WILLIS, D., et al., Inducible cyclooxygenase may have anti-inflammatory properties. Nature Medicine, 5, pp. 698–701, 1999.
7. DORMOND O., FOLETTI A., PAROZ C and RUEGG C., NSAIDs inhibit alpha-V beta-3 integrin-mediated and Cdc42/Rac-dependent endothelial-cell spreading, migration and angiogenesis. Nature Medicine, 7, pp. 1041–1047, 2001.
8. YIN, M-J., YAMAMOTO, Y., GAYNOR, R. B., The anti-inflammatory agents aspirin and salicylate inhibit the activity of I(kappa)B kinase-Beta. Nature, 396, pp. 77–80, 1998.
9. SAMAD, T. A., MOORE, K. A., SAPIRSTEIN, A., et al., Interleukin-1Beta-mediated induction of Cox-2 in the CNS contributes to inflammatory pain hypersensitivity. Nature, 410, pp. 471–475, 2001.
10. BUCCI, M., GRATTON, J.-P., RUDIC, R. D., et al., In vivo delivery of the caveolin-1 scaffolding domain inhibits nitric oxide synthesis and reduces inflammation. Nature Medicine. 6, pp. 1362-1367, 2000.
11. SAROSIEK, J., YU, Z., NAMIOT, Z., et al., Impact of acid and pepsin on human esophageal prostaglandins, American Journal of Gastroenterology, 89, 4, pp. 588-594, 1994.
12. ANSLEY, D.M., KARIM QAYUMI, A., DUNCAN, S., MERRICK, P.M., KLEIN, R., Platelet activating factor and thromboxane B2 production after cardiopulmonary bypass, Journal of Investigative Surgery, 10, 3, Pages 87-95, 1997.

MMP’s

1. PAGENSTECHER, A., WUSSLER, E.M., OPDENAKKER G., VOLK, B., CAMPBELL, I.L., Distinct expression patterns and levels of enzymatic activity of matrix metalloproteinases and their inhibitors in primary brain tumors. J. Neuropathol. Exp. Neurol., Jun 60:pp598-612, 2001.
2. LOBMANN, R., et al., Expression of MMP-8 and TIMP-2 in diabetic and non-diabetic wounds. Oral presentation given at the 36^th EASD annual meeting, 17^th-21^st September, Jerusalem, Israel, 2000.
3. HASLINGER, B., et al., Thrombin suppresses Matrix Metalloproteinase 2 activity and increases tissue inhibitor of Metalloproteinase 1 synthesis in cultured human peritoneal mesothelial cells. Peritoneal Dialysis International, 20 (6), pp.778-783, 2000.
4. YOSHIJI, H., et al., Tissue inhibitor of Metalloproteinases-1 promotes liver fibrosis development in a transgenic mouse model. Hepatology, 32 (6), pp.1248-1254, 2000.
5. LICHTINGHAGEN, R., et al., Expression of Matrix Metalloproteinase-2 and –9 and their inhibitors in peripheral blood cells of patients with chronic Hepatitis C. Clin. Chem., 46 (2) pp.183-192, 2000.
6. BELLUCCI, W, J., et al., A new screening assay for the evaluation of inhibitors of Matrix Metalloproteinases. In Vitro Cell. Dev. Biol-Animal. 35 (3), Part II, 1999.
7. LEIN, M., et al., Analytical aspects regarding the measurement of metalloproteinases and their inhibitors in blood. Clin. Biochem., 30, pp.491-496, 1997.
8. BAUGH, M., et al., Monocyte matrix metalloproteinase production in Type 2 diabetes and controls. Poster presented at the 36^th EASD annual meeting, 17^th-21^st September, Jerusalem, Israel, 2000.

1. CORSET, V., et al., Netrin-1 mediated axon outgrowth and cAMP production requires interaction with aenosine A2b receptor. Nature, 407, pp.747-750, 2000.
2. MENTZ, F., et al., Theophylline-induced B-CLL apoptosis is partly dependent on cyclic AMP production but independent of CD38 expression and endogenous IL-10 production. Leukemia, 13, pp.78-84, 1999.
3. HOLLOPETER, G., et al., Identification of the platelet ADP receptor targeted by antithrombotic drugs. Nature, 409, pp.202-207, 2001.
4. FELIPO, V., et al., Role of nitric oxide and of cGMP in glutamate-induced neuronal death. Invited symposium:reactive oxygen species and neurodegenerative diseases, 6^th internet world congress for biomedical sciences, 1999.
5. CABRELE, C., et al., The first selective agonist for the Neuropeptide YY₅ receptor increases food intake in rats. J. Bio. Chem., 275 (46), pp.36043-36048, 2000.
6. VILABOA, N, E., et al., cAMP incerasing agents prevent the stimulation of heat-shock protein 70 (HSP70) gene expression by cadmium chloride in human myeloid cell lines. J.Cell.Science, 108, pp.2877-2883, 1995.
7. FRIEDMAN, A.A., Anti-cancer effect of broccoli: selective inhibition of transformed mammalian cell growth by Brassica oleracea extract. Saint Andrew's Episcopal School, Ridgeland, MS 39157, 1997.
8. O’DONNELL, V, B., et al., Catalytic consumption of nitric oxide by Prostaglandin H Synthase regulates platelet function. J. Bio. Chem., 275 (49) pp.38239-38244, 2000.
9. GRAHAM, M, K., et al., Ionic mechanisms underlying spontaneous muscle contractions in the liver fluke, Fasciola hepatica. The American Physiology Society, 6, pp. R374-383, 1999.
10. BRAAS, K, M., and MAY, V. Pituitary adenylate cyclase-activating polypetides directly stimulate sympathetic neuron neuropeptide Y release through PAC₁ receptor isoform activation of specfic intracellular signaling pathways. J. Bio. Chem., 274 (39) pp.27702-27710, 1999.
11. MAEHAMA, T and DIXON, J E., The tumor suppressor, PTEN/MMAC₁, dephosphorylates the phophatidylinositol 3,4,5-triphosphate. J. Bio. Chem., 272 (22), pp.13375-13378, 1998.
12. TERHZAZ, S., et al., Isolation and characterization of a leucokikin-like peptide of Drosophila melanogaster. J. Exp. Bio., 202, pp.3667-3676, 1999.
13. BOYD, A, P., et al., Yersinia enterocolitica can deliver Yop proteins into a wide range of cell types: development of a delivery system for heterologous proteins. Eur. J. Cell Bio., 79, pp.659-671, 2000.
14. KOJIMA, M., et al., Ghrelin is a growth-hormone-releasing acylated peptide from stomach Nature, 402, pp.656-660, 1999.
15. DRAB, M., PAUL, V., ELGER, M., et al., Loss of Caveolae, Vascular Dysfunction, and Pulmonary Defects in Caveolin-1 Gene-Disrupted Mice. Science 293, pp. 2449-2452, (2001).
16. SATTLER, R., XIONG, Z., LU, W.-Y., HAFNER, M., MACDONALD, J. F. and TYRMIANSKI, M., Specific Coupling of NMDA Receptor Activation to Nitric Oxide Neurotoxicity by PSD-95 Protein. Science. 284, pp. 1845-1848, (1999).
17. MIYAZAKI, T. and REED, J. C., A GTP-binding adapter protein couples TRAIL receptors to apoptosis-inducing proteins. Nature Immunology. 2, pp.493–500, (2001).
18. JAFFREY, S. R. and SNYDER, S. H., PIN: An Associated Protein Inhibitor of Neuronal Nitric Oxide Synthase. Science. 274, pp. 774-777,(1996).
19. WANG B., KUSPA, A., Development in the Absence of cAMP. Science, 277, pp.251-254, (1997).
20. CHEN, Y., CANN, M. J., LITVIN, T. N., et al., Soluble Adenylyl Cyclase as an Evolutionarily Conserved Bicarbonate Sensor. Science, 289, pp. 625-628, (2000).
21. ZHENG, B., MA, Y. C., OSTROM, R. S. et al., RGS-PX1, a GAP for GalphaS and sorting nexin in vesicular trafficking. Science, 294(5548), p.1939-42, (2001).
22. KUNER, R., KÖHR, G., GRÜNEWALD, S. et al., Role of Heteromer Formation in GABAB Receptor Function. Science, 283, pp. 74-77, (1999).
23. MURTRA, P., SHEASBY, A. M., HUNT, S. P. and DE FELIPE, C., Rewarding effects of opiates are absent in mice lacking the receptor for substance P. Nature, 405, pp. 180–183, (2000)
24. WANG, Y., SMALL, D. L., STANIMIROVIC, D. B. et al., AMPA receptor-mediated regulation of a Gi-protein in cortical neurons. Nature, 389, pp. 502–504, (1997)
25. GAUSS, R., SEIFERT R. AND KAUPP, U. B., Molecular identification of a hyperpolarization-activated channel in sea urchin sperm. Nature. 393, pp.583–587, (1998).
26. FABRE, J. E., NGUYEN, M., LATOUR, A. et al., Decreased platelet aggregation, increased bleeding time and resistance to thromboembolism in P2Y1-deficient mice. Nature Medicine. 5(10), pp. 1199–1202, (1999).
27. ROHRER, S. P., BIRZIN, E. T., MOSLEY, R. T. et al., Rapid Identification of Subtype-Selective Agonists of the Somatostatin Receptor Through Combinatorial Chemistry. Science. 282, pp. 737-740, (1998).
28. KUBO, Y., MIYASHITA, T. AND MURATA, Y. Structural Basis for a Ca2+-Sensing Function of the Metabotropic Glutamate Receptors. Science, 279, pp. 1722-1725, (1998).
29. OHTA, A. AND SITKOVSKY, M. Role of G-protein-coupled adenosine receptors in downregulation of inflammation and protection from tissue damage. Nature, 14, pp. 916–920, (2001).
30. MEYER, C. J., ALENGHAT, F. J., RIM, P. et al., Mechanical control of cyclic AMP signaling and gene transcription through integrins. Nature Cell Biology. 2, pp.666–668, (2000).
31. ABDEL-MAJID, R. M., LEONG, W. L., SCHALKWYK, L. C. et al., Loss of adenylyl cyclase I activity disrupts patterning of mouse somatosensory cortex. Nature Genetics, 22, pp. 305–308. (1999).
32. WANG, Y., SMALL, D. L., STANIMIROVIC, D. B. et al., AMPA receptor-mediated regulation of a Gi-protein in cortical neurons. Nature. 389, pp. 502–504, (1997).
33. MURTRA, P., SHEASBY, A. M., HUNT, S. P. AND DE FELIPE, C., Rewarding effects of opiates are absent in mice lacking the receptor for substance P. Nature. 405, pp. 180–183, (2000).
34. JUTEL, M., WATANABE, T., KLUNKER S. et al., Histamine regulates T-cell and antibody responses by differential expression of H1 and H2 receptors. Nature. 413, pp.420–425, (2001).
35. ICHIKAWA, T., SUZUKI, Y., CZAJA, I. et al., Identification and role of adenylyl cyclase in auxin signalling in higher plants. Nature. 390, pp. 698–701, (1997).

Signal Transduction

1. NISHIDA, M., et al., Ga _i and Ga _o are target proteins of reactive oxygen species. Nature, 408, pp.492-495, 2000.
2. HASSEL, M., et al., The level of expression of a protein kinase C gene may be an important component of the patterning process in Hydra. Dev. Genes Evol., 207, pp.502-514, 1998.
3. ASADA, S., et al., Effect of hydrogen peroxide on the metabolism of articular chondrocytes. Inflamm. Res., 48, pp.399-403, 1999.
4. ALMEDIA, C., and GOES, A.M., Human peripheral blood mononuclear cells stimulated by Schistosoma mansoni antigens: association between protein tyrosine kinases, mitogen-activated protein kinases and cytokine production. Parasitology International, 48, pp.255-264, 2000.
5. HUANG, S., MAHER, V.M., MCCORMICK, J.J. Involvement of intermediary metabolites in the pathway of extracellular Ca²⁺-induced mitogen-activated protein kinase activation in human fibroblasts. Cell Signal 11 (4), pp.263-274 1999.
6. WANG, F., et al., Reciprocal interactions between b 1-integrin and epidermal growth factor receptor in three-dimensional basement membrane breast cultures: a different perspective Proc. Natl. Acad. Sci. U S A., 95 (25), pp.14821-6, 1998.
7. POLISCHOUK, A, G., et al., DNA double strand break repair, DNA-PK and DNA ligases in two human squamous carcinoma cell lines with different radiosensitivity. Int. J. Radiat. Oncol. Biol. Phys., 43 (1), pp.191-8, 1999.
8. DRAB, M., PAUL, V., ELGER, M., et al., Loss of Caveolae, Vascular Dysfunction, and Pulmonary Defects in Caveolin-1 Gene-Disrupted Mice. Science 293, pp. 2449-2452, 2001.
9. SATTLER, R., XIONG, Z., LU, W.-Y., et al., Specific Coupling of NMDA Receptor Activation to Nitric Oxide Neurotoxicity by PSD-95 Protein. Science. 284, pp. 1845-1848, 1999.
10. MIYAZAKI, T. and REED, J. C., A GTP-binding adapter protein couples TRAIL receptors to apoptosis-inducing proteins. Nature Immunology. 2, pp.493–500, 2001.
11. JAFFREY, S. R. and SNYDER, S. H., PIN: An Associated Protein Inhibitor of Neuronal Nitric Oxide Synthase. Science. 274, pp. 774-777, 1996.
12. OFFERMANNS, S., TOOMBS, C. F., HU, Y.-H. and SIMON, M. I., Defective platelet activation in G alpha (q)-deficient mice. Nature. 389, pp. 502–504, 1997.
13. LI, W.-H., LLOPIS, J., WHITNEY, M., ZLOKARNIK, G. and TSIEN, R. R. Y., Cell-permeant caged InsP3 ester shows that Ca²⁺ spike frequency can optimize gene expression Nature. 392, pp. 936-941, (1998).
14. CORSET, V., et al., Netrin-1 mediated axon outgrowth and cAMP production requires interaction with aenosine A2b receptor. Nature, 407, pp.747-750, 2000.
15. WANG B., KUSPA, A., Development in the Absence of cAMP. Science, 277, pp.251-254, 1997.
16. CHEN, Y., CANN, M. J., LITVIN, T. N., et al., Soluble Adenylyl Cyclase as an Evolutionarily Conserved Bicarbonate Sensor. Science, 289, pp. 625-628, 2000.
17. ZHENG, B., MA, Y. C., OSTROM, R. S. et al., RGS-PX1, a GAP for GalphaS and sorting nexin in vesicular trafficking. Science, 294 (5548), p.1939-42, 2001.
18. KUNER, R., KÖHR, G., GRÜNEWALD, S. et al., Role of Heteromer Formation in GABAB Receptor Function. Science, 283, pp. 74-77, 1999.
19. MURTRA, P., SHEASBY, A. M., HUNT, S. P. and DE FELIPE, C., Rewarding effects of opiates are absent in mice lacking the receptor for substance P. Nature, 405, pp. 180–183, 2000.
20. WANG, Y., SMALL, D. L., STANIMIROVIC, D. B. et al., AMPA receptor-mediated regulation of a Gi-protein in cortical neurons. Nature, 389, pp. 502–504, 1997.
21. GAUSS, R., SEIFERT R. AND KAUPP, U. B., Molecular identification of a hyperpolarization-activated channel in sea urchin sperm. Nature. 393, pp.583–587, 1998.
22. FABRE, J. E., NGUYEN, M., LATOUR, A. et al., Decreased platelet aggregation, increased bleeding time and resistance to thromboembolism in P2Y1-deficient mice. Nature Medicine. 5 (10), pp. 1199–1202, 1999.
23. ROHRER, S. P., BIRZIN, E. T., MOSLEY, R. T. et al., Rapid Identification of Subtype-Selective Agonists of the Somatostatin Receptor Through Combinatorial Chemistry. Science. 282, pp. 737-740, 1998.
24. KUBO, Y., MIYASHITA, T. AND MURATA, Y. Structural Basis for a Ca2+-Sensing Function of the Metabotropic Glutamate Receptors. Science, 279, pp. 1722-1725, 1998.
25. OHTA, A. AND SITKOVSKY, M. Role of G-protein-coupled adenosine receptors in downregulation of inflammation and protection from tissue damage. Nature, 14, pp. 916–920, 2001.
26. MEYER, C. J., ALENGHAT, F. J., RIM, P. et al., Mechanical control of cyclic AMP signaling and gene transcription through integrins. Nature Cell Biology. 2, pp.666–668, 2000.
27. ABDEL-MAJID, R. M., LEONG, W. L., SCHALKWYK, L. C. et al., Loss of adenylyl cyclase I activity disrupts patterning of mouse somatosensory cortex. Nature Genetics, 22, pp. 305–308. 1999.
28. MURTRA, P., SHEASBY, A. M., HUNT, S. P. AND DE FELIPE, C., Rewarding effects of opiates are absent in mice lacking the receptor for substance P. Nature. 405, pp. 180–183, 2000.
29. JUTEL, M., WATANABE, T., KLUNKER S. et al., Histamine regulates T-cell and antibody responses by differential expression of H1 and H2 receptors. Nature. 413, pp.420–425, 2001.
30. ICHIKAWA, T., SUZUKI, Y., CZAJA, I. et al., Identification and role of adenylyl cyclase in auxin signalling in higher plants. Nature. 390, pp. 698–701, 1997.
31. HOLLOPETER, G., JANTZEN, H.-M., VINCENT, D. et al., Identification of the platelet ADP receptor targeted by antithrombotic drugs. Nature. 409, pp. 202–207, 2001.
32. TOPHAM, M. K., BUNTING, M., ZIMMERMAN, G. A. et al., Protein kinase C regulates the nuclear localization of diacylglycerol kinase-zeta. Nature, 394, pp. 697–700, 1998.
33. LEIN, M., NOWAK, L., JUNG, K., et al., Analytical aspects regarding the measurement of metalloproteinases and their inhibitors in blood, Clinical Biochemistry, 30, 6, pp. 491-496, 1997.
34. Protein kinase C in rat brain cortex and hippocampus: Effect of repeated administration of fluoxetine and desipramine, British Journal of Pharmacology, 115, 4, pp. 595-600, 1995.
35. Activation of protein kinase C during cell volume regulation in Ehrlich mouse ascites tumor cells, Biochimica et Biophysica Acta - Molecular Cell Research, 1222, 3, pp. 477-482, 1994.

Cell Proliferation

1. MENG, X., LINDAHL, M., HYVONEN, M. E., et al., Raatikainen-Ahokas, A., Sainio, K., Rauvala, H., Lakso, M., Pichel, J. G., Westphal, H., Saarma, M. and Sariola, H., Regulation of Cell Fate Decision of Undifferentiated Spermatogonia by GDNF. Science. 287, pp. 1489-1493, 2000.
2. CHUANG, L. S-H. IAN, H., KOH, T., et al., Human DNA-(Cytosine-5) Methyltransferase-PCNA Complex as a Target for p21WAF1. Science. 277, pp. 1996-2000 1997.
3. PENG, C., GRAVES, P. R., THOMA, R. S., et al., Mitotic and G2 Checkpoint Control: Regulation of 14-3-3 Protein Binding by Phosphorylation of Cdc25C on Serine-216. Science. 277, pp. 1501-1505, 1997.
4. MILLS, A. D., COLEMAN, N., MORRIS, L. S. and LASKEY, R. A., Detection of S-phase cells in tissue sections by in situ DNA replication. Nature Cell Biology. 2, pp. 244–245, 2000.
5. VANHAESEBROECK, B., JONES, G. E., ALLEN, W. E., et al., Distinct PI(3)Ks mediate mitogenic signalling and cell migration in macrophage. Nature Cell Biology. 1, pp. 69–71, 1999.
6. JACOBS, J. J. L., KIEBOOM, K., MARINO, S., et al., The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus. Nature. 397, pp. 164–168, 1999.
7. MULAC-JERICEVIC, B., MULLINAX, R. A., DEMAYO, F. J., L., et al., Subgroup of Reproductive Functions of Progesterone Mediated by Progesterone Receptor-B Isoform. Science. 289, pp. 1751-1754, 2000.
8. KORINEK, V., BARKER, N., MOERER, P., VAN DONSELAAR, E., et al., Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4. Nature Genetics, 19, pp. 379–383, 1998.
9. MERALDI, A. P., LUKAS, J., FRY, A. M., et al., Centrosome duplication in mammalian somatic cells requires E2F and Cdk2-Cyclin Nature Cell Biology. 1, pp. 88–93, 1999.
10. RONN, L. C. B., OLSEN, M., ØSTERGAARD, S., et al., Identification of a neuritogenic ligand of the neural cell adhesion molecule using a combinatorial library of synthetic peptides. Nature Biotechnology. 17, pp. 1000–1005, 1999.
11. HOLASH, J., MAISONPIERRE, P. C., COMPTON, D., et al., Vessel Cooption, Regression, and Growth in Tumors Mediated by Angiopoietins and VEGF. Science. 284, pp. 1994-1998, 1999.
12. VISWANATHAN, A., YOU, H. J. and DOETSCH, P. W., Phenotypic Change Caused by Transcriptional Bypass of Uracil in Nondividing Cells. Science. 284, pp. 159-162, (1999).
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