GE Healthcare Life Sciences - Application notes

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Fast determination of plasmid DNA quantity and quality in complex solutions

The PlasmidSelect Xtra Screening Kit can be used to quickly and accurately determine plasmid DNA quantity and quality in complex solutions during fermentation and purification process development. ...

PlasmidSelect Xtra for downstream processing of supercoiled plasmid DNA

A generic, three-step chromatographic process for purifying high-quality supercoiled (sc) plasmid DNA (pDNA) based on PlasmidSelect Xtra medium was developed for a 6.2 kb plasmid on the prepacked ...

Upstream clarification, Key process factors for cross flow filtration

This Application Note describes variables you should consider in order to develop successful cross flow filtration upstream clarification processes using GE Healthcare hollow fiber cartridges. ...

Validation study for the removal/inactivation of viruses during a chromatographic purification process for Albumin and IgG

The purpose of this study was to demonstrate the ability of both a euglobulin precipitation/ion exchange chromatography step and a 60°C 10 hour pasteurization step to remove or inactivate a range of ...