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Downstream processing of antibody molecules

Practical course on the downstream processing of antibody molecules using chromatographic techniques.

Introduction to processing of antibodies – development and manufacturing issues
Physico-chemical properties of antibodies and antibody sources
Strategies for downstream processing of antibodies
Chromatographic techniques used in the downstream processing of antibodies
Strategies for the optimization of the individual chromatographic steps
Extensive practical session, taking the participants through three chromatographic steps for purification of a human IgG antibody expressed in CHO cell culture
Discussion of validation and regulatory issues related to the purification process of antibodies, e.g. leachables and column lifetime

Duration: 3.5 days
Course code: MAB1

Read more in the course description(PDF) for North America or Europe.

For course locations and dates, see course schedules.

Registrations North America
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Registrations Europe
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